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Polycyclic aromatic Hydrocarbon-Mediated mucosal irritation Polycyclic aromatic hydrocarbons (PAHs) represent some of the most problematic compounds found in tobacco smoke, as they possess both direct toxic effects and the ability to generate reactive oxygen species within gastric tissues

The tibial nerve was then crushed 23 mm distal to the trifurcation for 30 s by a small arterial microclip with smooth protective pads formed by silicon tubing placed over the blades

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