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Prescribing a nerve-calming medication without identifying the root cause (diabetes, vitamin B12 deficiency, tarsal tunnel compression, small fiber neuropathy, or erythromelalgia) delays the correct intervention

Vitamin B12 injections have multiple benefits

GHK-Cu degrades when mixed with ascorbic acid at low pH: the redox chemistry strips the copper(II) coordination, making combination serums at pH below 4.5 problematic

Methylfolate is the source of the methyl group that methionine synthase uses for converting homocysteine to methionine