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Hartlage-Rubsamen M, Bluhm A, Moceri S, Machner L, Koppen J, Schenk M, et al
The hemehuman AFHPX complexes produced a fainter punctate signal on the HepG2 cells than the rabbit HPX complexes, necessitating the use of higher concentrations
This has led some researchers to target 9mg rather than 12mg as their maintenance dose, especially given that the difference (2.3 percentage points) may not justify the additional side effect burden for all individuals
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Furthermore, it remains uncertain whether the signature gene expression pattern observed in mouse models truly represents human pathology when comparing expression patterns in human patient samples, and how reversible trained DAM memories are
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