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Considering the fact that it is not the resveratrol that reaches targeted tissues but its metabolites, those molecules should be the focus of research in future as a treatment for DS

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Although H 2 S production was not directly measured, increased levels of SAMan allosteric CBS -activatorin arterial cord blood in severe IPTB cases, regardless of treatment (and in venous blood, especially following NAC-treatment) suggest a potential role of SAM in counterregulatory responses

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ABR thresholds were determined 7 days post-treatment at 3 frequencies (4, 8, and 16 kHz)