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Moreover, user behaviors such as frequency of use, puffing patterns, motivation to use, and e-cigarette dependence may also result in individual variations in physiological responses

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Data collected from the Global Youth Tobacco Survey (GYST) 20102020 in 144 countries for a total of 432969 adolescents, the highest proportion of cigarette smoking initiation (36.8%) was at age 1213 years, followed by 1415 years (21.6%), and the average age of cigarette smoking initiation decreased or remained unchanged in nearly three-quarters of the countries surveyed 33

All tobacco is harmful