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The aim of this study is to leverage data from the Global Burden of Disease 2021 database to conduct an assessment of temporal trends and epidemiological patterns of smoking-attributable neurodegenerative diseases, Alzheimers disease, other dementias, and multiple sclerosis, across global, regional, and national scales, with a particular focus on age- and sex-stratified disparities

PMC 2563637

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Tobacco leaves have always been incredibly popular among the indigenous people of the Americas, with archaeological evidence suggesting that medicinal, recreational, and spiritual use of the plant dates back over 12 thousand years