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BPC 157 peptides anti-inflammatory properties and support for connective tissue integrity might benefit people with osteoarthritis, joint stiffness from overuse, inflammatory joint conditions, or those experiencing age-related joint changes

These include the severity of deficiency, patient age, and malabsorption issues

In the years immediately following the IOMs 1998 report setting the current RDA, research associated an abnormally high level of homocysteine, a molecule involved in protein metabolism, with an increased risk of cardiovascular disease, mortality, and cognitive impairment

However, some comparative studies in animals suggest that oral ingestion of the peptide can also have systemic effects

A reader who wants to evaluate the underlying papers can search PubMed for "GHK-Cu", "Thymosin beta 4 wound", "BPC-157 tendon" and "BPC-157 angiogenesis" to find the canonical entry points