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Physiol., 2010

Finally, the solvents used for extraction and the methods used to characterize kava extracts are of utmost importance to obtain a detailed fingerprint of each extract used and is needed to conduct future investigations

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5-amino-1MQ showed concentration-dependent inhibition of NNMT in fully differentiated adipocytes that could be fit to a 3-parameter sigmoidal dose-response curve with a calculated EC 50 = 2.3 +/ 1.1 M (Figures 2E, 2F