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Quitting smoking is so hard because of the complex interplay between physical addiction to nicotine and the psychological habits formed around tobacco use, as studied in an article by the Centers for Disease Control and Prevention titled Why Quitting Smoking Is Hard. Physically, nicotine creates dependence by altering brain chemistry, leading to withdrawal symptoms such as irritability, cravings, and anxiety when a person tries to quit

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As clumsy as they may be, theyve managed to roll up the Hot 100 three times via Jack and Jill song titles

They also usually use nicotine salts, which have a lower pH and therefore can deliver a higher dosage of nicotine to the user without as much irritation

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