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TABLE 2 Summary of recent studies of drugs that may be helpful in improving tamoxifen resistance

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Remarkably, immune checkpoint inhibitor (ICI) treatment targeting the PD-1/PD-L1 pathway is highly effective for metastatic mismatch repair-deficient and microsatellite instability-high (d-MMR/MSI-H) CRC 6

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It is common to feel a mild cooling sensation in the arm as room-temperature fluid enters the vein, or a brief metallic taste with certain vitamins both are normal and temporary