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It has been documented that short-term and long-term exposures often produce different results 47

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Moreover, VUF5202 has a completely different chemical scaffold compared to the known H 4 R antihistamines JNJ7777120 and Toreforant 32 , both of which didnt succeed in clinical trials 9 , highlighting the potential of developing innovative antihistamines for H 4 R via this new structural insight