PTT employs light-sensitive nanomaterials to convert light energy into heat, generating localized high temperatures to induce cancer cell apoptosis (Chen et al
Additionally, treatment with NAC + oe-VWF led to decreased VWF expression, levels of IL-6 and TNF-, and protein levels of Collagen I and -SMA as compared to treatment with oe-VWF alone (Fig
In addition, recent studies suggest that under certain conditions, such as hyperreduced CoQ pools and elevated mitochondrial membrane potential, reverse electron transport may occurwhereby electrons flow from ubiquinol (CoQ 10 H 2 ) back to complex I, generating NADH 110,111
These events lead to liver damage by loss of cell membrane integrity
The TMA and TMAO calibration curves were obtained by adding a known amount of D9-TMA or D9-TMAO to all dilutions of the TMA or TMAO standards, respectively