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GR-2397 has shown rapid fungicidal activity in murine aspergillosis models, and Phase 1 clinical trials demonstrated it is safe and well-tolerated (Rubino et al.,

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Golgi-associated S protein may be identified for retrograde trafficking by its association with Golgi-resident CoV M proteins 3,12 , consistent with its dependence on cis-Golgi-located M protein for incorporation into virions 6,12

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