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Consistent with the idea that this axis is required for resistance to DNA-damaging agents, knockdown of either CrAT or CrOT, which decreased histone acetylation (Extended Data Fig

However, this RR did not remain significant after further adjustment for the presence of the apolipoprotein E 4 allele, homocysteine concentration, and education level (RR, 1.24 [95% CI, 0.97-1.59

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Oral administration may offer convenience though injectable remains standard