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Chronic exposure to this smoke causes metaplastic alterations to the respiratory mucosa with an increase in the number and size of goblet cells and consequent increase in upper airway secretion.17,18 Cohen et al.13 and Kreindler et al.19 also showed in vitro that exposure to cigarette smoke inhibits chloride transport in epithelial cells, causing physiological alterations similar to those found in patients with cystic fibrosis

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SAINT LAURENT Saint Laurent Smoking Box cigarette holder in black leather Collector Square Ref: 36 84 75 This item is no longer available Get notified by email as soon as its available : Description Chic Saint Laurent Smoking Box cigarette holder in black leather, hardware in silver metal, one chain strap in silver metal allowing the bag to be worn on the shoulder or accross the body