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[87] GABA analogues: pregabalin, gabapentin, [88] picamilon, progabide 4-Amino-1-butanol is a biochemical precursor of GABA and can be converted into GABA by the actions of aldehyde reductase (ALR) and aldehyde dehydrogenase (ALDH) with -aminobutyraldehyde (GABAL) as a metabolic intermediate

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Elevated IGF-1 feeds back to suppress further GHRH release, which limits how far the axis can be driven

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