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Neurodegenerative diseases including multiple sclerosis, Parkinson's disease, and Alzheimer's disease show preliminary preclinical evidence of BPC-157 benefits

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For context on SAMe and related evidence limits, see the NIH NCCIH resource S-Adenosyl-L-Methionine (SAMe): In Depth

On the systems-level, the cerebellar nuclei outputs directly regulate movement signals in the brainstem and spinal cord, boost motor commands in the cerebral cortex via the thalamus, and modulate signals for adaptive learning through inhibitory projections to the inferior olive

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