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If a hospital's written request for low-volume hospital status for FY 2024 is received after September 1, 2023, and if the MAC determines the hospital meets the criteria to qualify as a low-volume hospital, the MAC would apply the low-volume hospital payment adjustment to determine the payment for the hospital's FY 2024 discharges, effective prospectively within 30 days of the date of the MAC's low-volume hospital status determination
Future research is expected to elucidate the mechanism of action HDAC inhibitors in order to design novel reagents with increased effectiveness and specificity
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Observed variability could be due to intrinsic variability of synapses (e.g., of the ratios of NMDA/AMPA receptors and calcium permeable/impermeable AMPA receptors across synapses within the same type of connection) and also to differences in experimental conditions and plasticity induction protocols (see Box 3 and Table 1) as well as animal lines and age and possible biases in sampling of highly heterogeneous inhibitory neurons
