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This framework underpins the agencys regulatory approach, which requires all new nicotine products to demonstrate that they are appropriate for the protection of public health before they can be legally sold

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However, more research is necessary

(1994) [52], along with multiple studies [53,54,55,56,57], have consistently shown that self-reports of smoking are highly reliable in large-scale population studies, suggesting that biochemical verification may not be necessary in such contexts [57]

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