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Guo F, Liu M, Zhu K, Ru J, Li P, Zhang S (2024) Esculetin modulates SLC31A1 and ATP7B to influence copper homeostasis and trigger cell death in colorectal cancer

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Because IGFBP-3 limits the availability of IGF-1, which stimulates cellular growth and proliferation

Clarkson, B, Gee T, Arlin Z, Mertelsmann R, Kempin S, Dinsmore R, O'Reilly R, Andreeff M , Berman E, Higgins C, Little C, Cirrincione C, Ellis S