We hypothesized that if melatonin suppresses ILC2s via NRF2 activation, then pharmacological activation of NRF2 with DMF should phenocopy the effects of melatonin
Troncoso R, Espinoza C, Snchez-Estrada A, Tiznado M, Garia HS (2005) Analysis of the isothiocyanates present in cabbage leaves extract and their potential application to control Alternaria rot in bell peppers
Acta A Mol
In 1992 it was demonstrated that a group of 289 subjects with workplace chemical exposure had quantitative and qualitative alterations at the cellular level (T and B lymphocytes and NK cells), such as abnormal T4/T8 ratios, elevated T cell (CD3 + ) and B cell (CD19 + ) numbers, activated T cells (CD10 + , CD15 + , CD26 + , CD38 + ), suppressed T cell and B cell function, and abnormal NK cell cytotoxic activity
It is important to note that the physico-chemical properties (e.g., complex formation, nucleophilic reactivity, redox properties) and biological functions of glutathione could be significantly different at different protonation states (i.e., in solutions with different pH values) [90,91,92,93] and its redox behavior [94,95]
