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Meanwhile, MR can also downregulate genes involved in an inflammatory response and immune cell infiltration, such as chemokine receptor (CCRs), chemokine ligand 7 (CCL7), IL-1, IL-6, IFN-, and TNF-

Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA1 but not VLA-4 integrin mediated human T-cell adhesion